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Sciex NanoLC 400 Series
The NanoLC 400 series enables a full range of analytical workflows that drive the identification of novel biomarkers or the quantification of small molecules and biologics to advance precision medicine research.
This front-end system consistently delivers accurate retention times, reproducible injection down to 200 nL and covers a broad range of flow rates.
The NanoLC 400 Series is available in two models, with patented pumps that make these systems among the most accurate nanoflow models on the market. Combined with industry-leading SCIEX mass spectrometers, the NanoLC Series provides high sensitivity, robustness and ease of use to support the latest in data-independent quantitative proteomics with SWATH® Acquisition.
The NanoLC 425 is an ideal HPLC system for labs performing a broad range of proteomics analyses. The additional pump gives you the power to dive deeper into your sample – with the ability to see more using 2D workflows. With the flexibility to have pre-set nano and microflow configurations, this 2-in-1 system is ideal for labs with diverse applications that need to actively switch between flow regimes. Like the NanoLC 415, this integrated system includes an autosampler, solvent organizer, sample storage and cooling; plus a column oven – helping your lab to realize its full potential.
When your sample is limited, and sensitivity is needed choose the NanoLC 415 for direct-to-column or trap-and-elute workflows. The NanoLC 415 is a complete package, providing an autosampler, solvent organizer, sample storage and cooling giving you the confidence that you will be up and running quickly.
| Key features | NanoLC 400 Series |
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| Models | NanoLC 415 for basic direct-to-column or trap-and-elute workflows NanoLC 425 for more advanced 2D workflows |
| Column Oven | Compatible with the OptiFlow® Turbo V coumn oven. Column oven provides excellent retention time reproducibility by ensuring consistent column temperature |
| Flow Rates | Multiple flow rate options with user-interchangable plug-and-play flow modules to switch between nanoflow (100 nl/min – 1 µl/min) and microflow (1 – 10, or 5 -50 µl/min) |
| Flow Accuracy | SCIEX’s patented multifluidic flow control technology, for consistent, accurate retention times without flow-splitting |
| Software | Integrated and controlled with SCIEX Analyst® Software |
